Quantitative monitoring of fundus changes

The proposed method allows to discover and quantify small changes in series of fundus photographs which are normally not directly comparable. The principle of geometric conformality of small parts between the fundus and its photographs is developed into a practical method of stereoscopic measurement, numerical adjustment and quantitative evaluation. Very high accuracy is possible without special conditions on repeated fundus photography. The aim is to create a theoretical and methodical basis for ophthalmoscopic change detection with image-processing computers.