Alkali exposure: an evidence-based approach to diagnosis and treatment

Alkali caustic exposures can occur in the workplace with industrial chemicals, or in the home with common household products. These exposures, whether accidental or intentional, create risk for death or acute injury, such as airway compromise and esophageal or gastric perforation, as well as long-term complications such as stricture formation. Swift diagnosis and grading of these injuries will guide management options and are essential to reduce morbidity and mortality in these patients. This issue reviews the evidence on emergency department management of alkali caustic exposures, with a focus on decontamination, resuscitation, and appropriate disposition.