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Antibiotic Use and Subsequent Cognitive Decline and Dementia Risk in Healthy Older Adults

Yiqing Wang1, Zhen Zhou1, Jonathan C Broder1

  • 1From the Clinical and Translational Epidemiology Unit (Y.W., A.T.C.), and Division of Gastroenterology (Y.W., A.T.C.), Massachusetts General Hospital and Harvard Medical School, Boston; School of Public Health and Preventive Medicine (Z.Z., J.C.B., R.L.W., S.G.O., R.W., J.R.), Monash University, Melbourne; Menzies Institute for Medical Research (Z.Z.), University of Tasmania, Australia; Department of Pharmacy Practice and Science (E.J.E.. M.E.E.), College of Pharmacy, and Department of Family Medicine (M.E.E.), Carver College of Medicine, University of Iowa, Iowa City; Department of Immunology and Infectious Diseases (A.T.C.), Harvard T.H. Chan School of Public Health, Boston; and Cancer Center (A.T.C.), Massachusetts General Hospital, Boston, MA.

Neurology
|December 18, 2024
PubMed
Summary

Antibiotic use in older adults did not increase the risk of dementia or cognitive decline. This study found no link between antibiotic exposure and long-term cognitive health outcomes in initially healthy individuals.

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