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Malignant vasovagal syncope in children

Wen-Rui Xu1, Hong-Fang Jin1,2, Jun-Bao Du3,4

  • 1Department of Pediatrics, Children's Medical Center, Peking University First Hospital, No. 8, Xishiku Street, West District, Beijing, 100034, China.

World Journal of Pediatrics : WJP
|December 18, 2024
PubMed

Insights

Malignant vasovagal syncope (VVS) in children is a serious condition involving prolonged asystole. Understanding its causes and effective treatments requires further investigation due to limited current research.

Area of Science:

  • Pediatric Cardiology
  • Neurology
  • Syncope Syndromes

Background:

  • Malignant vasovagal syncope (VVS) is a distinct cardioinhibitory VVS subtype.
  • It is characterized by prolonged asystole in pediatric patients.
  • This review focuses on malignant VVS in children.

Purpose of the Study:

  • To review advancements in understanding malignant VVS in children.
  • To explore potential pathogenesis, diagnostics, clinical significance, and treatment controversies.
  • To address the limited current knowledge on pediatric malignant VVS.

Main Methods:

  • Literature review of studies up to September 2024.
  • Databases searched include PubMed and Chinese Journal Full-text Database.
  • Search terms focused on "malignant vasovagal syncope" and "children" or "vasovagal syncope" with "asystole" and "children".

Main Results:

  • Studies on malignant VVS in children are limited.
  • Children with malignant VVS may be at risk of physical or mental impairment.
  • The mechanism of cardiac inhibition and optimal treatment strategies remain unclear.

Conclusions:

  • Current understanding of malignant VVS in children is insufficient.
  • Further research is needed on clinical features and pathogenesis.
  • Effective management strategies for pediatric malignant VVS require development.
Abstract

Keywords:
AsystoleDiagnosisPathogenesisPediatricsTreatmentVasovagal syncope

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