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Psychogenic fever and neurodevelopmental disorders among Japanese children
Ayumi Okada1,2,3, Yoshie Shigeyasu4,5, Chikako Fujii4,5
1Department of Pediatrics, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan. doidoi@cc.okayama-u.ac.jp.
Insights
Psychogenic fever in children is often linked to stress and school difficulties. Many cases involve neurodevelopmental disorders, highlighting the need for tailored diagnosis and treatment approaches.
Area of Science:
- Pediatric Psychosomatic Medicine
- Child Psychology
- Neurodevelopmental Disorders
Background:
- Psychosocial stress can manifest as physical symptoms, including fever, particularly in children.
- Unexplained fevers in pediatric patients may indicate psychogenic fever.
- Children with neurodevelopmental disorders are at higher risk for stress-induced somatic symptoms.
Purpose of the Study:
- To characterize children diagnosed with psychogenic fever.
- To identify comorbidities associated with psychogenic fever in pediatric patients.
- To explore the relationship between neurodevelopmental disorders and psychogenic fever.
Main Methods:
- Retrospective chart review of 21 pediatric patients with psychogenic fever.
- Data collected included demographics, diagnosis, comorbidities, treatment, and outcomes.
- Patients were treated at the Department of Pediatric Psychosomatic Medicine, Okayama University Hospital.
Main Results:
- The study included 14 girls and 7 boys with a median age of 13.0 years.
- 19 patients had school absence, and all showed school maladjustment.
- Comorbidities included orthostatic dysregulation (4) and migraine (3); 9 patients had neurodevelopmental disorders.
Conclusions:
- Psychogenic fever in children frequently co-occurs with comorbidities, notably neurodevelopmental disorders like autistic spectrum disorder.
- Difficulties in social adjustment contribute to psychological stress in children with neurodevelopmental disorders.
- Understanding patient characteristics and environmental factors is key for accurate diagnosis and effective treatment of psychogenic fever.
Background:
Psychosocial stress can induce various physical symptoms, including fever, which is a commonly seen symptom in pediatric practice. In cases of unexplained fever, psychogenic fever should be considered as a potential cause. Children with neurodevelopmental disorders may be more vulnerable to stress and therefore more prone to developing somatic symptoms than their peers. This study aimed to elucidate the characteristics of children with psychogenic fever and comorbidity.
Methods:
This study included 21 patients with psychogenic fever who visited the Department of Pediatric Psychosomatic Medicine, Okayama University Hospital. Information on age, sex, disease onset, final estimated diagnosis, comorbidities, treatment course, and outcome was obtained from the patients' medical records.
Results:
Of the 21 patients included, 7 were boys and 14 were girls, and their median age was 13.0 (range: 8.6-14.6) years. A total of 19 patients had no attendance at school, and all patients showed signs of maladjustment in school. The comorbidities included orthostatic dysregulation (n = 4) and migraine (n = 3). Neurodevelopmental disorders were observed in nine patients, eight of whom were diagnosed after the initial visit. The mean treatment duration was 37.2 months. The outcomes were complete remission (n = 9), improvement (n = 4), discontinuation (n = 1), and referral to another physician (n = 7).
Conclusion:
Various comorbidities were observed in the patients of this study with psychogenic fever, including the coexistence of neurodevelopmental disorders, such as autistic spectrum disorder. Children with neurodevelopmental disorders are prone to psychological stress resulting from difficulties in social adjustment. It is crucial to understand the developmental characteristics and environmental adaptation of patients to facilitate accurate diagnosis and treatment.
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