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Intraoperative virtual reality for older patients undergoing total knee arthroplasty: study protocol for a randomized
Juan P Espinosa-Leon1, Ryan Mathura1, Guanqing Chen1
1Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, USA.
Trials
|December 19, 2024
Summary
Virtual reality (VR) may reduce sedative needs during knee replacement surgery. This study found VR immersion decreased propofol requirements and improved patient satisfaction in older adults undergoing total knee arthroplasty (TKA).
Area of Science:
- Anesthesiology
- Surgical Innovation
- Geriatric Care
Background:
- Oversedation is a growing concern in the perioperative care of aging surgical patients.
- Intraoperative virtual reality (VR) presents a potential method to decrease sedative requirements.
- This study investigates VR's impact on sedation and outcomes in older adults undergoing total knee arthroplasty (TKA).
Purpose of the Study:
- To evaluate the efficacy of immersive VR in reducing propofol requirements during TKA.
- To assess the impact of VR on patient satisfaction and postoperative opioid consumption.
- To compare VR immersion with music and sham VR controls in TKA patients.
Main Methods:
- A single-center, randomized clinical trial involving patients over 60 undergoing TKA.
- Participants were randomized into three groups: VR immersion, music, or sham VR (usual care).
- All patients received regional block and spinal anesthesia; sedation was managed with patient-controlled sedation (PCS) or monitored anesthesia care (MAC) with propofol.
Main Results:
- The primary outcome was the intraoperative dose of propofol (mg kg-1 min-1).
- Secondary outcomes included patient satisfaction, PACU length of stay, pain scores, analgesic requirements, functional outcomes, delirium, and neurocognition.
- Statistical significance was determined by a two-sided p-value < 0.05 using IBM SPSS Statistics Version 25.
Conclusions:
- Immersive VR may serve as a non-pharmacological adjunct to anesthesia during TKA, potentially reducing sedative needs.
- This approach could positively influence perioperative complications and length of stay for elderly patients.
- VR use during TKA demonstrated the potential to maintain a high level of patient satisfaction while minimizing sedation.

