Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chronic active hepatitis caused by nitrofurantoin: a case report].

H C Burger, J L Meiring, P J Nel

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |January 26, 1985
    PubMed
    Summary

    Nitrofurantoin can cause chronic active hepatitis. This 79-year-old patient recovered after stopping the drug, highlighting the need for liver function tests during intermittent nitrofurantoin use.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Milk composition of free-ranging red hartebeest, giraffe, Southern reedbuck and warthog and a phylogenetic comparison of the milk of African Artiodactyla.

    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2016
    Same author

    Pathology and immunohistochemistry of papillomavirus-associated cutaneous lesions in Cape mountain zebra, giraffe, sable antelope and African buffalo in South Africa.

    Journal of the South African Veterinary Association·2011
    Same author

    Heart-vector and leads.

    British heart journal·2010
    Same author

    Descriptive study of an outbreak of equine sarcoid in a population of Cape mountain zebra (Equus zebra zebra) in the Gariep Nature Reserve.

    Journal of the South African Veterinary Association·2007
    Same author

    Capture and immobilisation of aardvark (Orycteropus afer) using different drug combinations.

    Journal of the South African Veterinary Association·2000
    Same author

    Ethics and the sanctity of human life.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·1998

    Area of Science:

    • Hepatology
    • Pharmacology
    • Internal Medicine

    Background:

    • Nitrofurantoin is a common antibiotic used for urinary tract infections.
    • Drug-induced liver injury (DILI) is a potential adverse effect of many medications.
    • Chronic active hepatitis is a long-term inflammatory liver condition.

    Observation:

    • A 79-year-old female patient developed chronic active hepatitis.
    • The condition was linked to the use of nitrofurantoin.
    • The patient's liver function normalized after discontinuing nitrofurantoin.

    Findings:

    • This case demonstrates nitrofurantoin as a potential cause of chronic active hepatitis.
    • Spontaneous recovery occurred upon drug withdrawal, suggesting a causal relationship.

    Related Experiment Videos

  • Liver function tests are crucial for monitoring patients on intermittent nitrofurantoin therapy.

    • Implications:

    • Clinicians should consider nitrofurantoin-induced liver injury in patients presenting with hepatitis.
    • Regular monitoring of liver function is recommended for individuals on intermittent nitrofurantoin treatment.
    • Early detection and drug withdrawal can lead to favorable patient outcomes.