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Updated: Jun 4, 2025

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
Premature hair graying: a multifaceted phenomenon
Deesha D Desai1,2, Maria Karim1, Ambika Nohria1
1The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY, USA.
Abstract:
Premature hair graying (PHG) is the early loss of natural hair color, influenced by genetic, biological, and environmental factors. This review discusses the significant psychological impacts of PHG and explores its underlying mechanisms, related health conditions, and available treatments. The review examines the roles of genetics, oxidative stress, and lifestyle factors such as smoking and diet in premature graying. It also considers associated medical conditions and current and emerging treatment options. This overview aims to improve understanding of PHG and its broader implications.
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