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Vaccination for solid organ transplanted patients: Recommendations, efficacy, and safety
Tsvetelina Velikova1, Stavros Gerasoudis2, Hristiana Batselova3
1Medical Faculty, Sofia University St. Kliment Ohridski, Sofia 1407, Bulgaria.
Abstract:
Solid organ transplant recipients face unique challenges in managing their immunosuppressed status, making vaccination a critical consideration. This review aimed to comprehensively analyze current recommendations, evaluate the efficacy of vaccinations in this population, and assess safety concerns. We explored the latest evidence on vaccine types, timing, and potential benefits for transplant patients, highlighting the importance of individualized approaches for routinely used vaccines as well as coronavirus disease 2019 vaccines. By synthesizing available data, this review underscored the pressing need to optimize vaccination strategies, ensuring that transplant recipients can obtain the full protection against many pathogens while minimizing risks associated with their post-transplant immunosuppression.
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