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Updated: May 6, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Modest dilation using rotational atherectomy and drug-coated balloon for native coronary proximal lesion with patent
Jun Shiraishi1, Takashi Mabuchi1, Takashi Kajihara1
1Department of Cardiology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
Insights
Percutaneous coronary intervention (PCI) on native proximal lesions is generally avoided in graft-protected arteries. Stent-less PCI using rotational atherectomy and drug-coated balloons may be a safe option for calcified lesions with patent bypass grafts.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Intervention in native proximal coronary arteries protected by bypass grafts carries a risk of graft failure.
- An 81-year-old male presented with worsening angina 17 years after coronary artery bypass grafting.
- Coronary angiography revealed significant lesions in a saphenous vein graft and the left main-proximal left anterior descending artery, with a patent right internal thoracic artery graft.
Abstract:
Intervention to proximal lesions should be avoided in graft-protected native coronary arteries in general, because there might be a risk for bypass-graft failure. An 81-year-old man with coronary artery bypass grafting surgery due to 3-vessel disease 17 years previously complained of worsening angina. Coronary angiography (CAG) revealed a diseased saphenous vein graft (SVG) and a probable functional occlusion in the mid left anterior descending coronary artery (LAD) concomitant with calcified severe stenosis in the left main (LM)-proximal LAD, and patent right internal thoracic artery (RITA)-LAD graft. After the first percutaneous coronary intervention (PCI) against the SVG lesion, we performed second PCI against the LM-proximal LAD lesions to release angina symptom and prevent LM occlusion. After rotational atherectomy (RA) with 1.5/1.75 mm burrs and balloon dilations, we detected a slight antegrade flow to distal LAD. To preclude possibility of graft failure in the RITA, we did not add further large-balloon dilations and stent implantations, and finally dilated with 3.0-mm drug-coated balloons (DCBs), leading to angina-free condition. Six-month follow-up CAG revealed no further vessel narrowing in both target vessels without RITA-graft failure. Stent-less PCI using relatively small-sized RA/DCB might be feasible for native proximal calcified lesions with patent bypass graft.
Learning Objectives:
•Full expansion of native proximal lesions should be avoided in internal thoracic artery (ITA) - protected coronary arteries in general, because it might provoke ITA-graft failure due to flow competition.•Stent-less modest dilation using relatively small-sized rotational atherectomy burr and drug-coated balloon might be a revascularization therapy of choice for native proximal calcified lesion with patent ITA bypass graft.
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