Related Experiment Video
Updated: Jun 4, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Development and efficacy of mobile application to improve medication adherence for persons with cardiac disease
Raziyeh Ghafouri1, Roxana Karbaschi2, AliReza Mashhadi Hosein3
1Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Insights
A new mobile app effectively improved medication adherence in heart patients. This intervention demonstrated significant benefits in patient compliance with treatment plans post-discharge.
Area of Science:
- Cardiology
- Digital Health
- Health Informatics
Background:
- Cardiovascular disease (CVD) management requires strict adherence to treatment plans.
- Poor medication adherence exacerbates CVD progression and reduces quality of life.
- Developing innovative tools is crucial for supporting patient self-management in cardiac care.
Purpose of the Study:
- To develop a mobile application tailored for patients with cardiac disease.
- To evaluate the efficacy of this mobile application in enhancing medication adherence.
- To assess the impact of the application on patient compliance with treatment recommendations.
Main Methods:
- The study utilized a two-stage approach, including mobile application development via the cascade model.
- 121 hospitalized cardiac patients were recruited and randomized into intervention (n=58) and control (n=63) groups.
- Medication adherence was assessed using a questionnaire on days 7, 14, and 21 post-discharge, with data analyzed using SPSS 20.
Main Results:
- No significant age difference was observed between the intervention (57.03 ± 11.55 years) and control (56.75 ± 11.38 years) groups.
- The intervention group showed significantly higher medication adherence on days 7, 14, and 21 post-discharge compared to the control group (P<0.01).
- Repeated measures analysis indicated a significant increase in adherence over time within the intervention group (P<0.001).
Conclusions:
- The developed mobile application is effective in improving medication adherence among patients with cardiac disease.
- Digital health interventions show promise for enhancing patient compliance in chronic disease management.
- This mobile tool can support cardiovascular patients in adhering to their prescribed treatment regimens.
Background:
Patients with cardiovascular disease need to adhere to their treatment and care recommendations to prevent the progression of their condition and improve their quality of life. In this regard, this study was conducted to develop a mobile application and test its effectiveness in improving medication adherence among persons with cardiac disease.
Methods:
The study was conducted in two stages. The first stage involved the preparation of the "Mobile Application for Persons with Cardiac Disease" using the cascade model. In the second stage, 121 patients who were hospitalized in the cardiac intensive care unit of Ayatollah Taleghani Medical Education Center of Tehran from March to August 2023 were enrolled. The participants were randomly assigned to either the control group (63 people) or the intervention group (58 people). The study collected data using a medication adherence questionnaire on the 7th, 14th, and 21st day after discharge and compared the results with the control group. The data were analyzed using SPSS 20.
Results:
The average age of the control group was 56.75 ± 11.38 years, and the average age of the intervention group was 57.03 ± 11.55 years. The comparison of the average medication adherence with independent t-tests showed a significant difference between the intervention and control groups on the 7th, 14th, and 21st day after discharge (P<0.01). The results of the repeated measures test in each group also showed that the difference between the groups increased over time (P<0.001).
Conclusion:
The results of the study showed that the mobile application is effective in improving medication adherence among heart patients.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Holter Monitor: 24-Hour Monitoring
Heart Failure Drugs: β-Blockers
Heart Failure Drugs: Inotropic Agents

