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Toward nanofabrication of SERS substrates with two-photon polymerization
Tatevik Chalyan1, Mehdi Feizpour1, Qing Liu1
1Brussels Photonics (B-PHOT), Department of Applied Physics and Photonics, Vrije Universiteit Brussel and Flanders Make Pleinlaan 2 B-1050 Brussels Belgium tatevik.chalyan@vub.be.
Nanoscale Advances
|December 19, 2024
Summary
This study introduces rapid, reproducible fabrication of surface-enhanced Raman spectroscopy (SERS) substrates using two-photon polymerization (2PP). These 2PP-printed SERS substrates offer significant Raman signal enhancement for molecular characterization.
Area of Science:
- Nanotechnology and Materials Science
- Spectroscopy and Analytical Chemistry
Background:
- Surface-enhanced Raman spectroscopy (SERS) enables single-molecule level characterization of biological substances.
- Nanofabrication technologies are crucial for developing and manufacturing SERS substrates.
Purpose of the Study:
- To report the complete cycle of design, fabrication, prototyping, and metrology of SERS substrates.
- To utilize two-photon polymerization (2PP) for creating advanced SERS substrates.
Main Methods:
- Employed two-photon polymerization (2PP) with direct laser writing for nanopillar fabrication.
- Achieved nanopillars with controllable aspect ratios up to 4.
- Evaluated substrate performance through Raman signal enhancement measurements.
Main Results:
- Developed SERS substrates demonstrated Raman signal enhancement up to 10^6, comparable to commercial options.
- Rapid prototyping achieved in minutes to under 2 hours, depending on design complexity.
- Exhibited well-controlled, reproducible fabrication yielding uniform nanostructure arrays.
Conclusions:
- Two-photon polymerization (2PP) is a viable and efficient method for SERS substrate fabrication.
- The developed substrates are suitable for broad applications in molecular characterization.
- The rapid and reproducible nature of 2PP printing facilitates versatile SERS applications.
