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Erectile dysfunction in men with human immunodeficiency virus: prevalence and associated factors
Suzane Skura1, Anna Martha Vaitses Fontanari2, Lia Beatriz Henke de Azevedo1
1Postgraduate Program in Applied Health Sciences, Western Paraná State University, Francisco Beltrão, Brazil.
Translational Andrology and Urology
|December 19, 2024
Summary
Erectile dysfunction (ED) affects 37.5% of men with HIV, linked to age, certain antiretroviral therapies, and anxiety. Integrated care addressing physical and mental health is crucial for managing ED in this population.
Area of Science:
- Men's Health
- Infectious Diseases
- Sexual Health
Background:
- Erectile dysfunction (ED) significantly impacts men's quality of life, particularly those living with human immunodeficiency virus (HIV).
- Understanding ED prevalence and associated factors in HIV-positive men is essential for targeted interventions.
Purpose of the Study:
- To determine the prevalence of ED in adult men living with HIV.
- To identify factors associated with ED in this population, including age, antiretroviral therapy (ART), and psychological elements.
Main Methods:
- A cross-sectional study involving 120 adult men with HIV in Paraná, Brazil.
- ED assessed using the International Index of Erectile Function (IIEF-6).
- Psychological factors evaluated with the Depression, Anxiety and Stress Scales-21 (DASS-21).
Main Results:
- The prevalence of ED was 37.5% (95% CI: 28.8%–46.2%).
- Significant associations found between ED and advanced age, specific ART regimens (NRTI+INI vs. NRTI+PI and NRTI+NRTI), and anxiety (OR=2.35).
Conclusions:
- Integrated clinical management addressing both medical and emotional health is vital for HIV-positive men with ED.
- Further longitudinal research is recommended to elucidate causal mechanisms of ED in men with HIV.
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