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Updated: Jun 4, 2025

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
Long-term chronic infection of a young immunocompromised patient by the SARS-CoV-2 P.2 VOI
Camila Malta Romano1, Vitor Gabriel Lopes da Silva2, Luciane Sussuchi da Silva3
1Universidade de São Paulo, Faculdade de Medicina, Instituto de Medicina Tropical de São Paulo, Laboratório de Virologia (LIM-52), São Paulo, São Paulo, Brazil.
Abstract:
An immunocompromised patient was infected by the SARS-CoV-2 variant of interest named Zeta (P.2) in February 2021. More than one year later, he suffered from symptomatic COVID-19 and sequencing revealed the same variant, which accumulated 23 substitutions. This case illustrates intra-host evolution of a particular SARS-CoV-2 variant, highlighting the importance of genomic surveillance of immunocompromised patients.
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