Experts' perspectives on human gene editing in Switzerland

Area of Science:

• Biotechnology
• Bioethics
• Medical Law

Background:

• Limited research exists on expert perspectives regarding Human Gene Editing (HGE).
• Understanding expert views is crucial for developing informed HGE policies and regulations.

Purpose of the Study:

• To explore Swiss experts' views on Human Gene Editing (HGE).
• To assess experts' expectations of Swiss public opinion on HGE.
• To identify factors influencing HGE perspectives within the unique Swiss context.

Main Methods:

• Exploratory interviews were conducted with 14 experts (scientists, clinicians, social scientists, lawyers) in Switzerland.
• Qualitative analysis of interview data explored expert opinions on Somatic Gene Editing (SGE) and Germline Gene Editing (GGE).

Main Results:

• General acceptance of Somatic Gene Editing (SGE) was observed.
• Opinions on Germline Gene Editing (GGE) were divided among experts.
• Participants highlighted the importance of patient autonomy, informed consent, and the need for clear regulations.
• Concerns were raised about potential healthcare outsourcing and medical tourism due to restrictive regulations on GGE.

Conclusions:

• Swiss expert opinions on HGE, particularly GGE, show nuances influenced by the national context.
• There is a recognized need for robust regulatory frameworks for HGE therapies.
• Cross-cultural research is essential to understand global attitudes towards HGE for tailored international regulations.