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Measurement of Energy Metabolism in Explanted Retinal Tissue Using Extracellular Flux Analysis
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Aged neurons don't register energy need

Deniz Bingul1, Scott F Owen1

  • 1Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.

Science (New York, N.Y.)
|December 19, 2024
PubMed
Summary

In aged mice, neuronal activity and mitochondrial gene expression become disconnected. This decoupling suggests a fundamental aging process affecting cellular energy regulation in the brain.

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