Multi-effect coupling enhanced PtPdRhFeCu HEA/N-Cu-ZnSe@C biosensing device for pesticide residue detection in fruits and vegetables with ultra-low detection limit

Dandan Song ¹, Guoqiang Li ¹, Qian Liu ¹

⁰Hebei Key Laboratory of Applied Chemistry, Key Laboratory of Heavy Metal Deep-Remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, China.

Food Chemistry +

|

December 19, 2024

View abstract on PubMed

Summary

An ultrasensitive electrochemical biosensor using novel high-entropy alloy nanotubes and dual-atom anchored materials offers highly sensitive pesticide detection. This innovation enhances food safety and environmental monitoring by enabling precise analysis of hazardous substances.

Area Of Science

Electrochemistry
Materials Science
Analytical Chemistry

Background

Accurate pesticide residue monitoring is crucial for food quality and human health.
Development of sensitive and efficient pesticide detection equipment is essential for practical applications.
Innovative analysis techniques are needed to meet stringent demands in food safety.

Purpose Of The Study

To develop an ultrasensitive electrochemical biosensor for pesticide residue detection.
To utilize quinary PtPdRhFeCu high-entropy alloy mesoporous nanotubes and N/Cu dual-atom anchored ZnSe@C as electrode materials.
To enhance pesticide analysis performance through multi-effect coupling and signal amplification.

Main Methods

Fabrication of an electrochemical biosensor using PtPdRhFeCu HEA mNTs and N-Cu-ZnSe@C electrode materials.
Leveraging multi-effect coupling (defect, high entropy, lattice distortion, doping) for enhanced electronic conductivity and electroactive surface area.
Utilizing acetylcholinesterase (AChE) for pesticide detection and signal amplification.

Main Results

Achieved ultra-low detection limits for aldicarb sulfone (2.32 fM) and methamidophos (4.58 fM).
Demonstrated wide detection ranges and high sensitivity and specificity for target pesticides.
Exhibited good recovery rates (86.67%–117.14%) in real sample analysis.

Conclusions

The developed biosensor offers a highly sensitive and efficient platform for pesticide residue analysis.
The signal amplification strategy integrating multiple material effects provides an innovative tool for hazardous substance detection.
This research contributes to advancements in intelligent pesticide detection equipment for food safety and environmental monitoring.

Keywords:

Dual-atom doping Electrochemical biosensing High-entropy alloys (HEA) Mesoporous nanotubes Pesticide residue