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Related Experiment Video

Updated: Jun 4, 2025

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Nonpharmacological Approaches to Chronic Cough.

Anne E Vertigan¹, Jemma Haines²

¹Speech Pathology Department, John Hunter Hospital, Newcastle, New South Wales, Australia; Centre for Asthma and Breathing, Hunter Medical Research Institute, Newcastle, New South Wales, Australia; School of Medicine and Public Health, College of Health and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.

The Journal of Allergy and Clinical Immunology. in Practice

|December 19, 2024

Summary

Speech pathologists offer nonpharmacological cough control therapy for chronic cough. This approach, involving education and urge suppression, shows promise for refractory cases and is increasingly recognized in guidelines.

Keywords:

Chronic cough Cough hypersensitivity Cough suppression Nonpharmacological Refractory chronic cough Unexplained chronic cough

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Area of Science:

Pulmonology and Speech-Language Pathology
Investigates the neurophysiological and behavioral aspects of chronic cough.

Background:

Chronic cough can persist despite medical treatment, often triggered by non-physical stimuli.
Nonpharmacological interventions, particularly cough control therapy (CCT), are emerging as a valuable option.

Purpose of the Study:

To review the efficacy and mechanisms of nonpharmacological interventions for chronic cough.
To highlight the role of speech pathology in managing refractory or unexplained chronic cough.

Main Methods:

Analysis of randomized controlled trials evaluating CCT.
Examination of key therapeutic components: education, urge anticipation and control, laryngeal irritation reduction, and psychoeducational counseling.

Main Results:

CCT has demonstrated efficacy in managing chronic cough, particularly in refractory cases.
Mechanisms of action are multifactorial, involving peripheral, central, and higher cortical pathways.

Conclusions:

Nonpharmacological CCT is supported by evidence and included in international guidelines for chronic cough management.
Standardization of CCT service delivery remains a challenge, with variations across regions and countries.