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Updated: May 6, 2026

Production and Purification of Non Replicative Canine Adenovirus Type 2 Derived Vectors
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Dutch bovine viral diarrhea virus control program: Evaluation 2018-2023.

E E C Strous1, P I H Bisschop1, G van Schaik2

  • 1Royal GD, 7418 EZ Deventer, the Netherlands.

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|December 19, 2024
PubMed
Summary

The Dutch national bovine viral diarrhea virus (BVDV) eradication program, offering four distinct routes, has proven successful. By 2023, BVDV-free dairy herds increased significantly, with fewer persistently infected cattle and reduced BVDV introductions.

Keywords:
BVDVcontrol programdairy cattleeradication

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Area of Science:

  • Veterinary Medicine
  • Animal Health
  • Epidemiology

Background:

  • Dutch dairy farmers must follow one of four routes for bovine viral diarrhea virus (BVDV) eradication since 2018.
  • Evaluating the national BVDV eradication program's effectiveness is crucial for dairy herd health.

Purpose of the Study:

  • To assess the efficacy of the Dutch national BVDV eradication program.
  • To analyze key indicators including persistently infected (PI) cattle, BVDV-free herd status, and BVDV reintroduction rates.
  • To conduct a cost calculation for each eradication route.

Main Methods:

  • Observational study design.
  • Monitoring the number of PI cattle quarterly.
  • Tracking the percentage of dairy herds achieving BVDV-free status.
  • Assessing BVDV reintroduction in BVDV-free herds.

Main Results:

  • The percentage of BVDV-free dairy herds rose from 59% to 89% by the end of 2023.
  • Quarterly detected PI cattle decreased from 500 to 83 between Q3 2019 and Q4 2023.
  • BVDV reintroduction in BVDV-free herds dropped from 1.29% to 0.25% per quarter.

Conclusions:

  • The Dutch BVDV eradication program, allowing multiple pathways, is highly successful.
  • The program effectively reduced BVDV prevalence and PI cattle in Dutch dairy herds.
  • Tailored national strategies, like the Dutch model, are effective for BVDV control in Europe.