[Research progress and prediction of quality markers of Menispermi Rhizoma]

Menispermi Rhizoma, the dried rhizome of Menispermum dauricum, has anti-tumor, anti-inflammatory, anti-arrhythmic, anti-myocardial ischemia, and anti-cerebral ischemia activities. The primary constituents of this herbal medicine include alkaloids, polysaccharides, and fatty oils. This study predicts and evaluates the quality markers(Q-markers) of Menispermi Rhizoma by considering the phylogenetic relationship of the plant, chemical composition, conventional effects, component measurability, blood constituents, and network pharmacology. The primary Q-markers of Menispermi Rhizoma are predicted to include daurisoline, dauricine, dauricumine, bianfugecine, epiberberine, tetrandrine, acutumidine, 6-O-demethylmenisporphine, and acutuminine. The findings hold potential for enhancing the quality evaluation system of Menispermi Rhizoma.