Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Analysis of Viral Blips Through Week 192 of the DRIVE-FORWARD and DRIVE-AHEAD Phase 3 Studies of Doravirine-Based Regimens in Adults Living With Previously Untreated HIV-1.

Open forum infectious diseases·2026

Same author

Revisiting gonorrhoea prevention in the era of resistance and biomedical interventions.

Sexually transmitted infections·2026

Same author

Knowledge, attitudes and behaviours in relation to doxycycline post-exposure prophylaxis use among attendees and healthcare workers at two sexual health services in Ireland.

Sexually transmitted infections·2026

Same author

Safety and Tolerability of Oral Islatravir Once Monthly as Pre-Exposure Prophylaxis in Cisgender Men and Transgender Women Who Have an Elevated Likelihood of HIV-1 Exposure: Results From the IMPOWER-24 Randomized Phase 3 Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026

Same author

Fixed-dose daily doravirine (100 mg) with islatravir (0·25 mg) versus bictegravir, emtricitabine, and tenofovir alafenamide for initial HIV-1 therapy: 48-week results of a phase 3, randomised, controlled, double-blind, non-inferiority trial.

The lancet. HIV·2026

Same author

Doravirine versus dolutegravir-based regimen in antiretroviral treatment-naive people living with HIV-1 (ANRS0392s ELDORADO): protocol for an international, open-label, randomised, non-inferiority, phase III trial.

BMJ open·2026

Search research articles

Related Experiment Video

Updated: Jun 4, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

Brief Report: Pancreatic Cancer in People With HIV: A Case-Control Study.

Sylvain Chawki^1,2,3, Gwenn Hamet⁴, Alexandre Brun⁴

¹UFR de Médecine, Université Paris Cité, Paris, France.

Journal of Acquired Immune Deficiency Syndromes (1999)

|December 20, 2024

Summary

This summary is machine-generated.

Pancreatic cancer (PC) is rare in people with HIV (PWH), with an incidence of 28 per 100,000 person-years. The study found PC in PWH has a poor prognosis, often diagnosed at a young age, with no significant risk factors identified.

More Related Videos

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Published on: January 3, 2013

Related Experiment Videos

Last Updated: Jun 4, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Published on: January 3, 2013

Area of Science:

Oncology
Infectious Diseases
Epidemiology

Background:

Pancreatic cancer (PC) risk in people with HIV (PWH) is not well-established.
Understanding PC incidence and risk factors in PWH is crucial for improved patient outcomes.

Purpose of the Study:

To estimate the incidence of pancreatic cancer (PC) in people with HIV (PWH).
To identify potential risk factors associated with PC development in PWH.

Main Methods:

A case-control study utilized electronic medical records from 2009-2020 for PWH in Paris.
Data included demographics, HIV treatment history, and immunovirologic status.
Cases (PWH with PC) were matched 1:4 with controls (PWH without PC) by age, gender, and HIV duration.

Main Results:

An incidence of 28 PC cases per 100,000 person-years was estimated.
Median age at diagnosis was 57 years; 88% were male.
Most patients had suppressed HIV replication, but 50% presented with metastasis; no significant risk factors were identified.

Conclusions:

Pancreatic cancer (PC) is rare but has a severe prognosis in people with HIV (PWH), often diagnosed at a younger age.
Further research is necessary to elucidate PC development risk factors in this population.