Research trends and key contributors in studies on influenza vaccines for children: A 20-year bibliometric analysis

Ning Sun1,2, Rui Wei1, Bochao Jia3

  • 1Department of Comprehensive Internal Medicine, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China.

PubMed

Insights

This study analyzes children's influenza vaccine research from 2004-2024. Future directions include international collaboration, addressing vaccine hesitancy, and developing live attenuated, intranasal, or universal influenza vaccines.

Area of Science:

  • Pediatrics
  • Immunology
  • Public Health

Background:

  • Influenza causes millions of severe cases and up to half a million deaths globally each year.
  • Children are particularly vulnerable to severe influenza complications.
  • Improving influenza vaccine coverage in children is critical for public health.

Purpose of the Study:

  • To conduct a comprehensive analysis of children's influenza vaccine research over the past 20 years (2004-2024).
  • To identify key contributors, research hotspots, and future trends in the field.
  • To explore strategies for enhancing vaccine coverage and addressing vaccine hesitancy.

Main Methods:

  • Data extraction from the Web of Science Core Collection (WOSCC) for publications between 2004 and 2024.
  • Bibliometric analysis to assess country, institution, author, and journal contributions.
  • Keyword analysis using CiteSpace and VOSviewer to predict research hotspots and future trends.

Main Results:

  • A total of 2,598 publications were analyzed.
  • The United States and England were the leading countries in research output.
  • AstraZeneca and Ambrose Christopher S were identified as key institutional and author contributors, respectively.
  • Journals 'Vaccine' and 'Human Vaccines & Immunotherapeutics' were prominent.

Conclusions:

  • International research collaboration is a promising strategy for global impact.
  • Addressing vaccine hesitancy is crucial for increasing vaccination coverage.
  • Future research should focus on live attenuated vaccines, intranasal administration, and universal influenza vaccines.