Infected Primary Bone Mantle Cell Lymphoma with Multiple Vertebral Involvement.

Area of Science:

• Oncology
• Hematology
• Radiology

Background:

• Primary vertebral lymphoma is exceptionally rare.
• Mantle cell lymphoma is an aggressive non-Hodgkin lymphoma.

Observation:

• A 67-year-old male presented with back pain, fever, and weight loss.
• Imaging revealed multiple vertebral lesions and a psoas abscess.
• Initial treatment focused on the abscess, with favorable outcome.

Findings:

• Vertebral biopsy confirmed bone mantle cell lymphoma.
• This is the first reported case of infected primary bone mantle cell lymphoma with extensive vertebral involvement.
• The presentation mimicked other spinal pathologies, complicating diagnosis.

Implications:

• Highlights the importance of considering rare malignancies in spinal pathology differentials.
• Emphasizes the need for thorough histopathological evaluation despite initial favorable responses to infection treatment.
• Underscores the diagnostic challenges associated with primary bone lymphomas.