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Pregnancy-Related Morphea: A Case Report.
Sedigheh Borna1, Zeynab Zamanpour2, Safoura Shakoei3
1Imam Khomeini Hospital, Family Health Research Institute, Vali-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Morphea, a skin condition causing hardened lesions, presented in a pregnant woman. While she recovered, predicting future pregnancy flare-ups remains challenging.
Area of Science:
- Dermatology
- Obstetrics
- Rheumatology
Background:
- Morphea is a localized sclerosing skin disorder characterized by inflammatory lesions.
- Pregnancy can sometimes trigger or exacerbate autoimmune and inflammatory conditions.
Observation:
- A pregnant patient presented with leg swelling, erythema, and a characteristic "orange peel" skin texture.
- Skin biopsy confirmed a sclerodermoid reaction pattern consistent with morphea.
- Symptoms worsened, necessitating a cesarean delivery and management with corticosteroids and mycophenolate mofetil.
Findings:
- The patient's morphea presentation during pregnancy resolved.
- Fetal well-being was maintained throughout the pregnancy, with normal biometry and Doppler studies.
- Postpartum follow-up showed resolution of skin inflammation and edema.
Implications:
- This case highlights the importance of recognizing morphea in pregnant patients.
- Management requires a multidisciplinary approach, balancing maternal and fetal health.
- Further research is needed to understand morphea's behavior during pregnancy and predict recurrence.
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