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Related Experiment Videos

Cross-allergenicity among the grasses.

B G Martin, L E Mansfield, H S Nelson

    Annals of Allergy
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    This study investigated grass allergen relationships using RAST inhibition. Timothy and Bermuda grass allergens were found to be significant, potentially explaining most cross-reactivity in other studied grasses.

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    Area of Science:

    • Immunology
    • Botany
    • Allergology

    Background:

    • Cross-allergenicity among different grass species is a significant concern for allergic individuals.
    • Understanding grass pollen allergen relationships can improve diagnosis and treatment strategies.
    • Botanical classification does not always align with observed allergenic patterns.

    Purpose of the Study:

    • To determine the allergenic relationships among various western, southern, and northern grass species.
    • To compare RAST inhibition patterns with established botanical classifications of grasses.
    • To identify key grass allergens responsible for cross-reactivity.

    Main Methods:

    • Radioallergosorbent test (RAST) inhibition was utilized to assess cross-allergenicity.
    • A panel of 14 grass species from different regions was studied.

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  • Allergenic patterns were analyzed and compared to botanical taxonomy.

    • Main Results:

    • Significant cross-allergenicity was observed across the studied grass species.
    • Brome, western wheat, and quack grasses showed allergenicity similar to northern grasses.
    • Salt and grama grasses were closely related to Bermuda grass, distinct from northern types.

    Conclusions:

    • Timothy and Bermuda grass allergens appear to be major contributors to cross-reactivity among the studied grasses.
    • Botanical classification is not a perfect predictor of grass allergen relationships.
    • Further research may be needed to fully elucidate the allergen profile of Bahia grass.