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Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
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Tracking cryptic SARS-CoV-2 hospital outbreak through quasispecies analysis

Serena Messali1, Marta Giovanetti2,3, Alessandro Rondina1

  • 1Department of Molecular and Translational Medicine, Section of Microbiology, University of Brescia, Piazzale Spedali Civili, 1, Brescia, 25123, Italy.

Virology Journal
|December 20, 2024
PubMed
Summary

Analyzing intra-host single nucleotide variants (iSNVs) in SARS-CoV-2 genomes enabled accurate identification of transmission chains among hospitalized patients. This genomic approach effectively traced virus spread within a hospital setting.

Keywords:
Hospital outbreakQuasispeciesSARS-CoV-2TraceabilityWGS

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