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Beyond hypertrophic cardiomyopathy: unmasking alternative causes of LVOT obstruction on CMR

Tanushree Banerjee1, Avanti Gulhane2, Aarohi Bhatt3

  • 1Cardiothoracic Imaging, Department of Radiology, University of Washington, Seattle, USA.

The International Journal of Cardiovascular Imaging
|December 21, 2024
PubMed

Insights

Takotsubo cardiomyopathy (TCM) can rarely mimic hypertrophic cardiomyopathy (HCM). This case highlights TCM presenting with left ventricular hypertrophy (LVH) and outflow tract obstruction (LVOTO) that resolved over time.

Area of Science:

  • Cardiology
  • Cardiovascular Medicine
  • Clinical Case Reports

Background:

  • Takotsubo cardiomyopathy (TCM) is characterized by transient left ventricular (LV) systolic dysfunction.
  • TCM typically mimics acute myocardial infarction but can rarely present atypically.
  • Mimicking hypertrophic cardiomyopathy (HCM) is an uncommon presentation of TCM.

Purpose of the Study:

  • To report a rare case of TCM mimicking HCM.
  • To describe the clinical presentation of TCM with left ventricular hypertrophy (LVH) and outflow tract obstruction (LVOTO).
  • To document the resolution of these findings on follow-up.

Main Methods:

  • Case study description.
  • Review of clinical presentation, echocardiography, and follow-up data.
  • Differential diagnosis considerations between TCM and HCM.

Main Results:

  • The patient presented with clinical and echocardiographic features of LVH and LVOTO.
  • These findings, initially suggestive of HCM, were attributed to TCM.
  • Resolution of LVH and LVOTO was observed during follow-up.

Conclusions:

  • TCM can present with features mimicking HCM, including LVH and LVOTO.
  • This presentation is rare but important to recognize for appropriate management.
  • Complete resolution of obstructive findings in TCM is possible.

Keywords:
Cardiac magnetic resonanceHypertrophic cardiomyopathyTakotsubo cardiomyopathy

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