Increased Infectious Risk Donor Status and Equity-Relevant Predictors of Organ Donation Organization Approach and Caregiver Consent for Deceased Organ Donation in a Canadian Province (2015-2021)
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View abstract on PubMed
Summary
This summary is machine-generated.Increased infectious risk donor (IIRD) status did not affect organ donation approach or caregiver consent rates. IIRDs were more likely to become successful donors, showing no increased infectious transmission risk in this cohort.
Area Of Science
- Transplantation Science
- Public Health
- Epidemiology
Background
- Current donor risk assessments face criticism for potential discrimination against sexual and gender minorities.
- Limited understanding exists regarding the deceased donation process for individuals with increased infectious risk donor (IIRD) status.
- This study addresses how IIRD status impacts organ donation approach and consent rates.
Purpose Of The Study
- To evaluate the impact of increased infectious risk donor (IIRD) status on the likelihood of deceased organ donation approach.
- To assess the influence of IIRD status on caregiver consent for organ donation.
- To examine equity-relevant identities in the deceased organ donation system.
Main Methods
- Retrospective, observational cohort study of potential deceased donors in a Canadian province (2015-2021).
- Primary outcome: Likelihood of organ donation organization (ODO) approach for IIRDs versus baseline risk donors.
- Secondary outcome: Caregiver consent for donation among approached donors; multivariable logistic regression models were used.
Main Results
- IIRD status did not significantly impact the likelihood of being approached for deceased organ donation (OR 1.695, 95% CI 0.902-3.197).
- No significant difference in caregiver consent for donation between IIRD and baseline risk donors (OR 1.854, 95% CI 0.902-3.929).
- IIRDs were younger, had fewer comorbidities, lower KDPI scores, and were more likely to have died from anoxic brain injuries.
Conclusions
- No significant difference was found in ODO approach rates for IIRDs compared to baseline risk donors.
- Caregiver consent rates for organ donation did not differ between IIRD and baseline risk donors.
- A higher proportion of IIRDs resulted in successful organ donations compared to baseline risk donors.
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