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Derivation and Validation of an Electronic Health Record Penicillin Allergy De-Labeling Prevalence Measure
Kimberly G Blumenthal1,2,3, Bohang Jiang3, Andrew J King3
1Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Abstract:
With no standard method to capture penicillin allergy de-labeling prevalence across populations, we developed and validated a simple penicillin allergy de-labeling prevalence measure from electronic health records that achieved perfect sensitivity (100.0%), high specificity (99.4%), and strong agreement with a comprehensive algorithm that included free-text manual review (kappa = .997).
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