Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurophysiological studies on workers exposed to lead.

J Jeyaratnam, G Devathasan, C N Ong

    British Journal of Industrial Medicine
    |March 1, 1985
    PubMed
    Summary

    Lead exposure in workers can cause subclinical neurological damage, detectable through nerve conduction and somatosensory evoked potential studies. These findings highlight the need for stricter monitoring of lead-exposed individuals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Strengthening service integration of non-locally trained healthcare professionals through crew resource management: longitudinal measures and beyond.

    Hong Kong medical journal = Xianggang yi xue za zhi·2025
    Same author

    Clarifying the absence of evidence regarding human health risks to microplastic particles in drinking-water: High quality robust data wanted.

    Environment international·2020
    Same author

    Rapid Microbiology Screening in Pharmaceutical Workflows.

    SLAS technology·2018
    Same author

    A nanobiosensor for dynamic single cell analysis during microvascular self-organization.

    Nanoscale·2016
    Same author

    Arctic cut-off high drives the poleward shift of a new Greenland melting record.

    Nature communications·2016
    Same author

    A Universal Electrode Approach for Automated Electrochemical Molecular Analyses.

    Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2014

    Area of Science:

    • Occupational Health
    • Neurotoxicology
    • Clinical Electrophysiology

    Background:

    • Lead exposure is a known neurotoxicant.
    • Assessing subclinical neurological effects in occupationally exposed populations is crucial.

    Purpose of the Study:

    • To evaluate neurological damage in lead-exposed workers using electrophysiological methods.
    • To determine the sensitivity of nerve conduction studies (NCS) and somatosensory evoked potentials (SEPs) in detecting lead-induced neuropathy.

    Main Methods:

    • Nerve conduction studies (NCS) and somatosensory evoked potentials (SEPs) were performed on 46 lead-exposed workers and controls.
    • Electroencephalograms (EEGs) were conducted on a subset of workers.
    • Blood lead concentrations were measured for all participants.

    Related Experiment Videos

    Main Results:

    • Lead-exposed workers showed significantly reduced motor conduction velocities and prolonged distal latencies in median and posterior tibial nerves.
    • No significant differences were observed in sensory nerve conduction for median and sural nerves.
    • SEPs demonstrated significant prolongations in both median and posterior tibial nerves.
    • EEG studies revealed no abnormalities.

    Conclusions:

    • NCS and SEPs are sensitive tools for detecting subclinical neurological damage from lead exposure.
    • Observed changes at a mean blood lead concentration of 2.35 mumol/l suggest a need for enhanced monitoring protocols for lead-exposed workers.