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Brucella anthropi bacteremia: Persistent bacteremia with minimal symptoms
Sho Yokota1, Toshibumi Taniguchi2, Shin Takayanagi2
1Department of Infectious Diseases, Chiba University Hospital, Chiba, Japan.
Summary
Brucella anthropi bacteremia can persist in stable patients, even with minimal symptoms. Follow-up blood cultures are crucial to confirm treatment effectiveness and ensure resolution of this opportunistic infection.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
Background:
- Brucella anthropi is an opportunistic pathogen, primarily affecting immunocompromised individuals.
- Systemic lupus erythematosus (SLE) is an autoimmune condition associated with increased infection risk.
Observation:
- A 27-year-old woman with SLE developed persistent Brucella anthropi bacteremia after pregnancy termination.
- The patient presented with minimal symptoms, including transient fever, despite ongoing bacteremia.
Findings:
- Initial treatment with ceftazidime failed due to Brucella anthropi resistance.
- Ciprofloxacin therapy successfully eradicated the persistent bacteremia.
- Symptom resolution did not correlate with bacteremia clearance, necessitating further monitoring.
Implications:
- This case highlights the diagnostic challenge of Brucella anthropi infections in non-specific presentations.
- Vigilant monitoring with follow-up blood cultures is essential for managing persistent bacteremia, even in clinically stable patients.
- Effective antibiotic selection, guided by susceptibility testing, is critical for treating Brucella anthropi infections.
