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Sleep quality and incident hypertension.

Zhihao Zheng1, Yanjun Song1, Zechen Liu1

  • 1Cardiometabolic Medicine Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; State Key Laboratory of Cardiovascular Disease, Beijing, China; National Clinical Research Center for Cardiovascular Diseases, Beijing, China.

Revista Espanola De Cardiologia (English Ed.)
|December 22, 2024
PubMed
Summary
This summary is machine-generated.

Poor sleep quality significantly increases hypertension risk. Longer sleep duration may reduce this risk for those with healthy or intermediate sleep. This finding holds true even with genetic predisposition.

Keywords:
BehaviorsCalidad del sueñoComportamientosCreencias sanitariasHealth beliefsHipertensiónHypertensionPublic healthSalud públicaSleep quality

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Area of Science:

  • Cardiovascular Health
  • Sleep Medicine
  • Public Health

Background:

  • Poor sleep quality is a global public health concern.
  • Hypertension is a leading risk factor for cardiovascular diseases.
  • Understanding modifiable risk factors like sleep is crucial for prevention.

Purpose of the Study:

  • To investigate the association between sleep quality and the risk of developing new-onset hypertension.
  • To examine the role of sleep duration in relation to hypertension risk.
  • To assess if this association is influenced by genetic predisposition to hypertension.

Main Methods:

  • Analysis of two large cohorts: UK Biobank (UKB) and English Longitudinal Study of Ageing (ELSA).
  • Inclusion of adults without baseline hypertension (UKB: 284,250; ELSA: 6,104).
  • Sleep quality assessed via questionnaires; sleep duration by self-reported hours.

Main Results:

  • Poor sleep quality was significantly associated with a higher risk of hypertension in both UKB (HR, 1.277) and ELSA (HR, 1.264) cohorts.
  • Prolonging sleep duration correlated with a decreased hypertension risk in individuals with intermediate or healthy sleep quality.
  • The link between poor sleep and increased hypertension risk remained significant, irrespective of genetic susceptibility.

Conclusions:

  • Poor sleep quality is an independent risk factor for elevated hypertension risk, even considering genetic predisposition.
  • Optimizing sleep duration, particularly for individuals with intermediate or healthy sleep quality, may mitigate hypertension risk.