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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Related Experiment Video

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Author Spotlight: Unlocking Insights into the Immune Cell Landscape of Tumors
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Physiological markers for immunotherapeutics: a review.

Durlav Chowdhury1, Ashmita Das1, Mrityunjay Mishra1

  • 1Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Chhattisgarh, India.

Journal of Chemotherapy (Florence, Italy)
|December 23, 2024
PubMed
Summary

Cancer immunotherapy utilizes diverse strategies like cytokines and cell transfer. Advanced techniques identify tumor microenvironments, paving the way for innovative, personalized cancer medicines.

Keywords:
BiomarkersICIScancerimmunotherapyproteomic biomarkers

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Area of Science:

  • Oncology
  • Immunology
  • Bioinformatics

Background:

  • Immunotherapy represents a significant advancement in cancer treatment.
  • Multiple therapeutic modalities exist, including immunogenic cytokines, monoclonal antibodies, therapeutic vaccinations, adoptive cell transfer, stem cell transplantation, and oncolytic viruses.

Purpose of the Study:

  • To review and analyze strategies for identifying tumor microbiota and microenvironments.
  • To highlight the role of advanced technologies in cancer immunotherapy research.

Main Methods:

  • Genomics and transcriptomics for molecular profiling.
  • Single-cell techniques for high-resolution analysis.
  • Computational analysis and big data approaches for interpretation.
  • Advanced imaging technologies for spatial context.

Main Results:

  • Identification of key tumor microbiota and microenvironment components.
  • Integration of multi-omics data for comprehensive understanding.
  • Demonstration of technological advancements in cancer research.

Conclusions:

  • Immunotherapy is a feasible and evolving cancer treatment modality.
  • Personalized medicine approaches are facilitated by understanding the tumor microenvironment.
  • Innovative cancer medicines are emerging from these advanced research strategies.