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Updated: Jul 18, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter ablation in grown-up congenital heart disease patients: A single-center experience
Stergios Soulaidopoulos1, Stella Brili1, Maria Drakopoulou1
1First Department of Cardiology, Hippokration General Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Insights
Catheter ablation (CA) is a safe and effective treatment for tachyarrhythmias in adults with congenital heart defects (CHD), improving functional capacity. This study highlights its benefits and long-term outcomes in managing complex cardiac conditions.
Area of Science:
- Cardiology
- Electrophysiology
- Adult Congenital Heart Disease
Background:
- Tachyarrhythmias are common in adults with congenital heart defects (CHD), leading to reduced functional capacity and increased morbidity.
- Catheter ablation (CA) is a potential treatment option for these complex arrhythmias.
Purpose of the Study:
- To evaluate the safety and efficacy of catheter ablation (CA) for tachyarrhythmias in adult patients with congenital heart defects (CHD).
- To present the clinical experience and long-term outcomes of CA in this specific patient population.
Main Methods:
- Retrospective analysis of 35 adult patients with CHD who underwent CA between 2002 and 2021.
- Application of modified ablation techniques tailored to individual patient anatomy.
- Monitoring of NYHA functional status and cardiac rhythm during follow-up.
Main Results:
- CA was performed for supraventricular and ventricular tachyarrhythmias in 35 adults with CHD.
- Most common diagnoses included atrial fibrillation/flutter, intra-atrial reentrant tachycardia, and atrioventricular nodal reentry tachycardia.
- No significant complications occurred during CA; 37.1% recurrence rate observed, with 6 redo procedures. Pacemaker or ICD implantation was required in some cases.
Conclusions:
- Catheter ablation (CA) is a safe procedure for managing tachyarrhythmias in adult CHD patients.
- CA effectively preserves functional capacity and offers significant benefits in this population.
Background:
Supraventricular and ventricular tachyarrhythmias represent a common complication in grown-up patients with congenital heart defects (CHD) associated with worsening of functional capacity and increased morbidity. The aim of this study was to present the experience of our department on catheter ablation (CA) addressing safety and efficacy concerns.
Methods:
Consecutive patients with CHD treated with CA between 2002 and 2021 in our hospital were included in this study. The established ablation techniques modified according to the patient's special anatomic characteristics were applied. NYHA functional status along with the underlying cardiac rhythm were recorded during the follow-up.
Results:
In total, 35 patients (44.9 ± 2.7 years, 22 males) underwent CA for the management of either supraventricular or ventricular (n = 2) arrhythmia during the study period. The most common anatomical diagnoses were atrial septal defect (13), Tetralogy of Fallot (5) and transposition of great arteries (3). Atrial fibrillation or atrial flutter was the most frequent baseline diagnosis, observed in 15 (42.8%) patients, followed by intra-atrial reentrant tachycardia in 9 (25.7%) patients and atrioventricular nodal reentry tachycardia (AVNRT) in 5 (14.2%). No significant complication occurred during CA. Patients were followed for a median period of 9 years after the index procedure. At this time, arrhythmia recurrence was observed in 13 patients (37,1%) of whom 6 underwent a redo procedure. Furthermore, 4 patients underwent a permanent pacemaker implantation, while 6 were offered an ICD treatment.
Conclusion:
CA is a safe method offering significant benefits regarding the management of tachyarrhythmias and preserving functional capacity in adult patients with CHD.
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