1,4-Di-methyl-piperazine-2,3-dione

Area of Science:

• Crystallography
• Organic Chemistry
• Structural Chemistry

Background:

• Piperazine-2,3-dione derivatives are important scaffolds in medicinal chemistry.
• Understanding the conformational preferences and intermolecular interactions of such compounds is crucial for drug design.

Purpose of the Study:

• To determine the crystal structure and molecular conformation of the title compound, C6H10N2O2.
• To investigate the intermolecular interactions present in the solid state.

Main Methods:

• Single-crystal X-ray diffraction was employed to analyze the crystal structure.
• Analysis of hydrogen bonding interactions was performed.

Main Results:

• The piperazine-2,3-dione ring was found to adopt a half-chair conformation.
• Molecules were observed to form (010) sheets via weak C-H⋯O hydrogen bonds.

Conclusions:

• The study elucidates the specific conformational behavior of this piperazine-2,3-dione derivative in the solid state.
• The identified hydrogen bonding network provides insights into crystal packing and potential intermolecular interactions relevant to related compounds.