Sinonasal Carcinoma With Aggressive Right Intraorbital Extension and Left Eye Invasion in a Young Female Patient

Sinonasal cancers are rare and aggressive head and neck malignancies. Sinonasal squamous cell carcinoma (SNSCC) typically affects males and individuals over the age of 55. Here, we present an unusual case of a young female diagnosed with SNSCC. She presented with painful right eye proptosis, rapid progressive vision loss in both eyes, and a history of intermittent epistaxis. MRI revealed an aggressive sinonasal mass with intra-orbital and intracranial extension, and a biopsy confirmed sinonasal non-keratinizing squamous cell carcinoma. Despite initial systemic chemotherapy, the patient discontinued treatment and, unfortunately, succumbed to the disease. This case highlights the aggressive nature and management challenges of advanced SNSCC, emphasizing the critical importance of early diagnosis and timely intervention to improve outcomes.