Related Experiment Video
Updated: May 5, 2026

07:02
Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice
Published on: August 24, 2011
14.8K
Intracranial Extramedullary Hematopoiesis Simulating a Subdural Hematoma: A Case Report
Wisam Al-Saad1, Pir Abdul Ahad Aziz Qureshi2,3, Vikram Rao Bollineni1,3
1Radiology, University Hospital Brussels, Brussels, BEL.
Cureus
|December 23, 2024
Summary
A patient with myeloproliferative disease presented with neurological symptoms. Initial imaging suggested subdural hematoma, but aspiration revealed extramedullary hematopoiesis, a rare complication.
Area of Science:
- Neurology
- Hematology
- Pathology
Background:
- Extramedullary hematopoiesis (EMH) is the formation of blood cells outside the bone marrow.
- It can occur secondary to various myeloproliferative diseases.
- EMH can present with diverse neurological symptoms, mimicking other conditions.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
34
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
34
Hemorrhagic Stroke ll: Pathophysiology
52
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
52
Cerebral Edema ll: Pathophysiology
31
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
31

