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Extended Reality Gaming for Exercise and Mindfulness Throughout Pediatric Cancer Rehabilitation: Protocol for a
Byron Lai1, Kelli Chaviano1, Joshua S Richman2
1Division of Pediatric Rehabilitation Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, United States.
JMIR Research Protocols
|December 23, 2024
Summary
This pilot study explores an extended reality (ER) program to improve physical and mental health in pediatric cancer patients undergoing bone marrow transplants. The 14-week program uses immersive gaming and mindfulness to enhance rehabilitation outcomes.
Area of Science:
- Rehabilitation Medicine
- Pediatric Oncology
- Digital Health
Background:
- Pediatric cancer patients face challenges in self-managing health during and after hospital treatment.
- Extended reality (ER) offers immersive solutions for pain management, mental health, and physical activity in clinical settings.
- No established ER protocol exists for pediatric cancer rehabilitation to improve both physical and mental health.
Purpose of the Study:
- To investigate the effects of a 14-week ER program on physical activity and health indicators in pediatric cancer patients post-bone marrow transplant.
- To assess the feasibility and participant engagement of the ER program.
Main Methods:
- A pilot randomized controlled trial with a 1-group crossover design involving 16 pediatric cancer patients (≥8 years).
- Two groups: immediate ER intervention (hospital and home) vs. waitlist control with usual care.
- Intervention includes active video gaming, mindfulness, and behavioral coaching; physical activity measured by accelerometry; health outcomes assessed using PROMIS scales and spirometry.
Main Results:
- Study funded Feb 2024, recruitment began June 2024.
- Data collection anticipated by Feb 2026, with results analyzed and submitted by March 2026.
- Anticipated study completion date is March 31, 2026.
Conclusions:
- This trial evaluates an accessible remote ER program designed to enhance physical and mental well-being in pediatric cancer patients.
- Findings will guide the development of larger clinical trials for this population.
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