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Updated: Jun 4, 2025
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Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells
Published on: November 17, 2017
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New era of plasma dentistry
Kotaro Sato1,2, Hiromasa Tanaka3, Yasumasa Okazaki2
1Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Free Radical Research
|December 23, 2024
Summary
Low-temperature plasma (LTP), a fourth physical state, offers medical and dental benefits. Research shows LTP applications in wound healing, cancer treatment, and general dentistry due to its oxidative stress effects.
Area of Science:
- Physics
- Engineering
- Medicine
- Dentistry
Background:
- Low-temperature plasma (LTP) represents the fourth physical state of matter, characterized by high energy and free radicals at near-body temperatures.
- Developed through engineering in the 1990s, LTP research has rapidly advanced in medical and engineering fields since the 2000s.
- LTP can be applied via direct or indirect exposure, each with distinct advantages.
Purpose of the Study:
- To review the medical and dental applications of low-temperature plasma.
- To highlight the effectiveness of LTP in various therapeutic areas, including wound healing, hemostasis, and anticancer treatments.
- To explore the potential of plasma dentistry in clinical practice.
Main Methods:
- Review of existing research on low-temperature plasma applications in medicine and dentistry.
- Analysis of LTP's effects, primarily mediated by oxidative stress levels.
- Evaluation of LTP's suitability for general dental procedures and oral cancer treatment.
Main Results:
- LTP demonstrates significant effects in wound healing, hemostasis, and anticancer therapies.
- Studies confirm LTP's efficacy in restorative, periodontal, and prosthodontic dental procedures.
- The oral cavity's anatomical characteristics facilitate direct observation, enhancing clinical applications of LTP.
Conclusions:
- Low-temperature plasma exhibits diverse therapeutic effects in medicine and dentistry.
- Plasma dentistry is poised for widespread clinical adoption due to its accessibility and efficiency.
- LTP's effectiveness is largely attributed to its ability to modulate oxidative stress.
Keywords:
Dentistryferroptosislow-temperature plasmaoral cancerplasma-activated ringer’s lactate solutionMore Related Videos
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