Recent Advances on Integrating Porous Nanomaterials with Chemiluminescence Assays

Advanced porous nanomaterials have recently been the subject of considerable interest due to their high surface areas, tunable pore structures, high porosity, and ease of modification. In the chemiluminescence (CL) domain, the incorporation of additional pores into nanostructures not only enhances the loading capacity for signal amplification but also allows the confinement effect in a nanoscale microreactor and the controlled release of reaction agents. In light of this, increasing efforts have been made to fabricate various porous nanomaterials and explore their potential applications in CL assays. This review therefore aims to highlight the recent advances in preparation strategies and basic attributes of the CL-related porous nanomaterials. Moreover, it offers a comprehensive summary of the emerging CL sensing applications based on these materials. The key challenges and future perspectives of porous nanomaterials in CL assays are finally discussed.