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Updated: Jun 4, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Periodontitis upon hypothyroidism of young people
Oksana M Repetska1, Zoryana B Popovych1, Iryna Z Chubiy1
1IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY, IVANO-FRANKIVSK, UKRAINE.
Objective:
Aim: To study the periodontal tissues and to establish the Magnesium content in oral liquid and capillary blood of young people with hypothyroidism from areas with Iodine deficiency.
Patients And Methods:
Materials and Methods: In order to study the prevalence of periodontal disorders there were 330 people aged from 25 to 44 years from areas with natural Iodine deficiency enrolled in this examination. Primary hypothyroidism was diagnosed in 195 people (they made up the group I), and 135 people did not have any accompanying endocrine pathology (group II). The most prevalent were 30-34-year-olds - 38,46% in the group I and 39,26% in the group II. Patients aged 25-29 years were the least: 27,18% and 28,89% in the I and II groups. Biochemical analysis of oral fluid and capillary blood was performed to investigate the Magnesium content.
Results:
Results: According to the results of the dental examination, it was established that 85,13% of young people with hypothyroidism were also affected by periodontal disorders. On the other hand, periodontal disorders were observed in 69,63% of people of the same age range without endocrine pathology (p<0,01). Chronic generalized periodontitis of I and II degree dominated in the spectrum of periodontal disorders. The concentration of Magnesium in the blood serum of individuals with hypothyroidism was lower than in those without hypothyroidism.
Conclusion:
Conclusions: The obtained data indicate a negative effect of primary hypothyroidism on the development of periodontal tissue diseases.
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