Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Cochlea01:13

The Cochlea

43.8K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
43.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The first report of contralateral parapharyngeal space metastasis of papillary thyroid carcinoma: report of a case.

Oral oncology·2026
Same author

Nasal saline irrigation with azelastine-fluticasone nasal spray in moderate-to-severe persistent allergic rhinitis: a randomized controlled trial.

Frontiers in allergy·2025
Same author

Stapokibart for Severe Uncontrolled Chronic Rhinosinusitis With Nasal Polyps: The CROWNS-2 Randomized Clinical Trial.

JAMA·2025
Same author

Knowledge map of programmed cell death in esophageal cancer: a bibliometric analysis.

Discover oncology·2025
Same author

Identification of the disulfidptosis-related key gene CD2AP as a potential biomarker and new therapeutic target for LUAD patients by comprehensive multi-omics analysis.

Discover oncology·2025
Same author

Mechanistic studies on the role of CHI3L1 in eosinophilic inflammation in chronic sinusitis.

Frontiers in immunology·2025

Related Experiment Video

Updated: May 8, 2025

A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis
08:06

A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis

Published on: March 19, 2021

2.7K

Advances in Microfluidic Cochlea-On-A-Chip.

Tian Shen1, Shanying Han2, Weiwei He2

  • 1Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|December 24, 2024
PubMed
Summary
This summary is machine-generated.

Cochlea-on-a-chip systems, using organoids and microfluidics, are advancing inner ear research. This technology aims to improve drug screening and understand developmental mechanisms for hearing disorders.

Keywords:
biomaterialscochlea‐on‐a‐chipdisease modelingdrug testingmanufacturing strategiesmicrofluidic organ‐on‐a‐chip

More Related Videos

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

20.9K
A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
11:32

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

Published on: November 23, 2015

13.6K

Related Experiment Videos

Last Updated: May 8, 2025

A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis
08:06

A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis

Published on: March 19, 2021

2.7K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

20.9K
A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
11:32

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

Published on: November 23, 2015

13.6K

Area of Science:

  • Biomedical Engineering
  • Otolaryngology
  • Developmental Biology

Background:

  • Current human auditory system research relies heavily on animal and cellular models.
  • Organoids mimic cochlear structures and functions, but developmental cues are poorly understood.
  • This knowledge gap hinders the development of advanced cochlea-on-a-chip systems.

Purpose of the Study:

  • To review recent advancements in cochlea-on-a-chip technology.
  • To summarize breakthroughs in 3D inner ear organoid cultivation.
  • To explore progress in microfluidic technologies for cochlea-on-a-chip construction.

Main Methods:

  • Review of current literature on cochlear anatomy and physiology.
  • Analysis of 3D organoid cultivation techniques for inner ear research.
  • Examination of microfluidic system designs for cochlea-on-a-chip platforms.

Main Results:

  • Overview of cochlear anatomy and physiology.
  • Discussion of 3D inner ear organoid cultivation advancements.
  • Exploration of microfluidic technology progress for cochlea-on-a-chip systems.

Conclusions:

  • Cochlea-on-a-chip platforms offer promising preclinical testing grounds.
  • Further research is needed to understand physical and chemical cues for organoid development.
  • Addressing current challenges will drive future cochlea-on-a-chip technology development.