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Serum Vitamin D Profiles of Children with Asthma in Southwest Saudi: A Comparative Cross-Sectional Study

Ali Alsuheel Asseri1

  • 1Department of Child Health, King Khalid University, Abha, 62529, Saudi Arabia.

International Journal of General Medicine
|December 24, 2024
PubMed

Insights

Vitamin D deficiency is highly prevalent in asthmatic children in Saudi Arabia, with over half showing deficiency. Older age and higher BMI predict lower vitamin D levels in these children.

Area of Science:

  • Pediatric Allergy and Immunology
  • Nutritional Biochemistry
  • Public Health

Background:

  • Vitamin D deficiency is linked to increased asthma prevalence and severity.
  • Asthma management requires understanding contributing factors like nutritional status.
  • Investigating vitamin D's role in pediatric asthma is crucial for public health.

Purpose of the Study:

  • To determine the prevalence of vitamin D deficiency in asthmatic children.
  • To assess the relationship between vitamin D status and asthma control/severity.
  • To identify predictors of vitamin D deficiency in pediatric asthma patients.

Main Methods:

  • A comparative cross-sectional study was conducted at a tertiary care hospital.
  • Serum vitamin D levels were measured in 331 asthmatic and 101 non-asthmatic children.
  • Statistical analyses included correlation and regression to identify predictors.

Main Results:

  • Asthmatic children had significantly lower vitamin D levels (21.5 ng/mL) than controls (33.3 ng/mL).
  • Vitamin D deficiency (51.1%) and insufficiency (34.7%) were significantly higher in asthmatic children.
  • Older age and higher BMI were independent predictors of lower vitamin D levels in asthmatic children.

Conclusions:

  • A high prevalence of vitamin D deficiency exists among asthmatic children in southwestern Saudi Arabia.
  • Vitamin D screening and supplementation are recommended for this population.
  • Targeted interventions for older, overweight asthmatic children may be beneficial.
Abstract

Keywords:
Saudi Arabiaasthmachildrenobesityvitamin D deficiency

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