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Evaluation of the early effect of elective percutaneous coronary intervention on left ventricular diastolic and
Seyed Abdolhossein Tabatabaei Tabatabaei1, Hakimeh Sadeghian1, Ramin Negin Taji1
1Department of Cardiology, Dr Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Insights
Percutaneous coronary intervention (PCI) improves early diastolic function and global longitudinal strain (GLS) within 1-2 days. However, PCI did not significantly impact global circumferential strain (GCS) in patients with coronary artery disease.
Area of Science:
- Cardiology
- Echocardiography
- Interventional Cardiology
Background:
- Percutaneous coronary intervention (PCI) is a standard treatment for coronary artery disease.
- Previous research indicates delayed effects of PCI on left ventricular function.
- The early impact of PCI on diastolic and systolic function, particularly global longitudinal strain (GLS) and global circumferential strain (GCS), remains under-examined.
Purpose of the Study:
- To investigate the early reversibility of diastolic and systolic abnormalities after PCI.
- To compare the effects of PCI on GLS and GCS in patients with significant coronary artery stenosis.
Main Methods:
- Eighty patients with normal left ventricular function undergoing elective PCI were included.
- Echocardiography was performed before and 1-2 days after PCI.
- Left ventricular diastolic and systolic function indices, including GLS and GCS, were assessed.
Main Results:
- Patients showed significant improvements in diastolic function indices and GLS 1-2 days post-PCI.
- No significant improvement was observed in GCS.
- The study cohort had a mean age of 58.0±11.9 years, with 65% males.
Conclusions:
- Early revascularization via PCI can improve left ventricular diastolic function and GLS within 1-2 days.
- PCI demonstrates no significant early impact on GCS.
- These findings highlight the rapid functional recovery of the left ventricle post-PCI.
Background:
Percutaneous coronary intervention (PCI) is an effective treatment for coronary artery disease. Previous studies have demonstrated the delayed effects of PCI on left ventricular diastolic and systolic function. However, the early impact on these parameters has not been systematically examined. Moreover, no study has compared the impact of revascularization on the global longitudinal (GLS) and circumferential (GCS) strains of the left ventricle. Using echocardiographic parameters, the present study aimed to investigate the reversibility of diastolic and systolic abnormalities in patients with significant coronary artery stenosis within 1 to 2 days after PCI. Additionally, this study will compare the effects on both global and longitudinal strains.
Methods:
This study included 80 consecutive patients admitted to the angiography department for elective PCI with normal left ventricular function. Echocardiography was performed before PCI and 1 to 2 days post-procedure to assess left ventricular diastolic and systolic function indices in these patients.
Results:
The mean age of the patients was 58.0±11.9 years, with a predominantly male cohort (65%). All the patients exhibited normal left ventricular systolic function and various degrees of diastolic dysfunction. One to 2 days after revascularization, significant improvements were observed in all diastolic function indices and GLS. However, no significant improvement was found in GCS.
Conclusion:
Revascularization of a significantly stenotic coronary artery can enhance diastolic function and systolic longitudinal strain of the left ventricular myocardium as early as 1 to 2 days, with no significant impact on GCS.
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