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Updated: May 8, 2025

Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
Lingual Actinomycosis Mimicking Lingual Squamous Cell Carcinoma (SCC)
Mohsen Meidani1, Hana Saffar2, Nahid Shafiee1
1Department of Infectious Disease, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
Actinomycosis is an infection caused by Actinomyces israelii and mainly affects cervicofacial areas. In women, other regions, such as the chest, abdomen, and pelvic cavity can involve actinomycosis. Actinomycosis lesions in the oral cavity can cause pain, swelling, induration, pus discharge, and discomfort similar to other benign or malignant pathologies. This condition can mimic lingual cancer, such as squamous cell carcinoma (SCC), which is highly invasive with a poor prognosis. It is necessary to distinguish actinomycosis from SCC and other malignancies to choose the proper treatment. The current study presents a patient with a suspicious lingual mass for SCC diagnosed as actinomycosis after partial glossectomy and pathological studies.
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