Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

334
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
334
Gas Chromatography–Mass Spectrometry (GC–MS)01:14

Gas Chromatography–Mass Spectrometry (GC–MS)

4.0K
Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a single instrument for analyzing a mixture of compounds. The gas chromatograph separates the compounds in the mixture, and the mass spectrometer analyzes each compound separately to determine the molecular masses and molecular structures.
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
4.0K
Gas Chromatography: Types of Detectors-I01:21

Gas Chromatography: Types of Detectors-I

373
There are different types of detectors used in gas chromatography, each with its own specific properties that make it suitable for detecting certain types of analytes. The most commonly used detectors in GC are thermal conductivity detector (TCD), flame ionization detector (FID), and electron capture detector (ECD).
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...
373
Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

425
Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...
425
Qualitative Analysis03:46

Qualitative Analysis

21.7K
For solutions containing mixtures of different cations, the identity of each cation can be determined by qualitative analysis. This technique involves a series of selective precipitations with different chemical reagents, each reaction producing a characteristic precipitate for a specific group of cations. Metal ions within a group are further separated by varying the pH, heating the mixture to redissolve a precipitate, or adding other reagents to form complex ions.
For instance, group IV...
21.7K
High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

470
The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte...
470

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient on-site detection of nitazenes in hair: Integrating MCX pipette-tip solid-phase extraction with miniaturized mass spectrometry.

Talanta·2026
Same author

An intelligent DNAzyme theranostic probe for <i>in situ</i> FTO bioimaging and real-time therapeutic efficacy evaluation in living cells.

The Analyst·2026
Same author

Bearings-only acoustic source localization method using two distributed gliders and deep ocean experimental validation in the South China Sea.

JASA express letters·2026
Same author

Integrated micro-solid-phase extraction with miniature mass spectrometry for on-site detection of illicit drugs in human hair.

Journal of chromatography. A·2026
Same author

Development of a Highly Effective Bifunctional Ligand 2E-C-NETA for Targeted Lu-177 Therapy: Synthesis, Radiolabeling, In Vitro Stability, and In Vivo Biodistribution.

ChemMedChem·2026
Same author

Atomic layer deposition for core-shell microparticle vaccines enabling programmable antigen delivery to lymph nodes enhance humoral immune responses.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Jun 4, 2025

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

10.0K

An effective method for detecting nitrous oxide using alkaline washing and GC-MS.

Mu Yang1,2, Wenqing Gao2,3, Liang Ma1,2

  • 1Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo, China. yujiancheng@nbu.edu.cn.

Analytical Methods : Advancing Methods and Applications
|December 24, 2024
PubMed
Summary

A new method uses alkaline washing to remove carbon dioxide (CO2) interference, enabling accurate detection of nitrous oxide (N2O) using gas chromatography-mass spectrometry (GC-MS). This simple technique achieves a low limit of detection for N2O monitoring.

More Related Videos

GC-based Detection of Aldononitrile Acetate Derivatized Glucosamine and Muramic Acid for Microbial Residue Determination in Soil
11:06

GC-based Detection of Aldononitrile Acetate Derivatized Glucosamine and Muramic Acid for Microbial Residue Determination in Soil

Published on: May 19, 2012

16.9K
On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes
07:49

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes

Published on: August 5, 2016

10.7K

Related Experiment Videos

Last Updated: Jun 4, 2025

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

10.0K
GC-based Detection of Aldononitrile Acetate Derivatized Glucosamine and Muramic Acid for Microbial Residue Determination in Soil
11:06

GC-based Detection of Aldononitrile Acetate Derivatized Glucosamine and Muramic Acid for Microbial Residue Determination in Soil

Published on: May 19, 2012

16.9K
On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes
07:49

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes

Published on: August 5, 2016

10.7K

Area of Science:

  • Environmental Chemistry
  • Analytical Chemistry

Background:

  • Nitrous oxide (N2O) detection is crucial for environmental monitoring.
  • Gas chromatography-mass spectrometry (GC-MS) is a common N2O detection method.
  • CO2 shares similar properties with N2O, complicating accurate N2O detection.

Purpose of the Study:

  • To develop a simple and effective method for N2O detection.
  • To eliminate CO2 interference in N2O measurements.
  • To enhance the accuracy of N2O monitoring using GC-MS.

Main Methods:

  • A novel approach combining alkaline washing with GC-MS was employed.
  • Alkaline washing was used to selectively remove CO2 from gas samples.
  • N2O was subsequently detected using GC-MS.

Main Results:

  • The alkaline washing effectively eliminated CO2 interference.
  • The limit of detection (LOD) for N2O was determined to be 0.01 μL mL-1.
  • The relative standard deviation (RSD) for N2O detection was below 10%.

Conclusions:

  • The proposed method offers a simple and effective solution for N2O detection.
  • It successfully removes CO2 interference without specialized equipment.
  • This technique shows significant promise for accurate N2O monitoring in various applications.