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Sigmoid diverticulitis with perforation and generalized peritonitis.

D M Nagorney, M A Adson, J H Pemberton

    Diseases of the Colon and Rectum
    |February 1, 1985
    PubMed
    Summary
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    Perforating sigmoid diverticulitis requires prompt surgical intervention. Resection or exteriorization with colostomy significantly reduces mortality compared to colostomy with drainage alone.

    Area of Science:

    • Gastroenterology
    • Surgical Oncology
    • Clinical Medicine

    Background:

    • Sigmoid diverticulitis with perforation and generalized peritonitis is a severe complication of diverticular disease.
    • Prompt surgical management is crucial for patient outcomes.

    Purpose of the Study:

    • To compare the efficacy of two surgical approaches for perforating sigmoid diverticulitis: proximal colostomy with drainage versus proximal colostomy with resection or exteriorization.
    • To identify factors predicting mortality in patients with this condition.

    Main Methods:

    • A retrospective analysis of 121 consecutive patients with perforating sigmoid diverticulitis was conducted.
    • Patients were divided into two groups based on surgical approach: colostomy with drainage (n=31) and colostomy with resection or exteriorization (n=90).

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  • Clinical and pathological features were assessed, and mortality rates were compared.
  • Main Results:

    • Overall mortality for emergency surgery was 12%.
    • Mortality was significantly higher in the colostomy and drainage group (26%) compared to the colostomy with resection or exteriorization group (7%) (P < 0.05).
    • Persistent postoperative sepsis, fecal peritonitis, preoperative hypotension, and prolonged symptom duration were predictive of mortality.

    Conclusions:

    • Proximal colostomy with resection or exteriorization is associated with significantly lower mortality rates for perforating sigmoid diverticulitis compared to colostomy with drainage.
    • Identifying high-risk patients through predictive factors can guide surgical strategy towards more definitive procedures for improved survival.