Dead cells don't form mutant colonies: a serious source of bias in mutation assays

Bell-shaped nuclei dividing by symmetrical and asymmetrical nuclear fission have qualities of stem cells in human colonic embryogenesis and carcinogenesis.

Cancer genetics and cytogenetics·2005

Combination of competitive quantitative PCR and constant-denaturant capillary electrophoresis for high-resolution detection and enumeration of microbial cells.

Applied and environmental microbiology·2001

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection.

Nature genetics·2001

Two-point fluorescence detection and automated fraction collection applied to constant denaturant capillary electrophoresis.

BioTechniques·2000

Identification of in vivo mutations in exon 5 of the human HPRT gene in a set of pooled T-cell mutants by constant denaturant capillary electrophoresis (CDCE).

Mutation research·2000

Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene.

Mutation research·2000

Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: observation of a positive response.

Environmental mutagenesis·1987

Mutagenesis of L5178Y/TK(+/-)-3.7.2C mouse lymphoma cells by the clastogen ellipticine.

Environmental mutagenesis·1987

Induction of sperm abnormalities in mice by quercetin.

Environmental mutagenesis·1987

The effect of cell passage on the susceptibility of BALB/3T3 clone A31-1-1 cells to 3-methylcholanthrene-induced morphological transformation.

Environmental mutagenesis·1987

Methyl isocyanate: an evaluation of in vivo cytogenetic activity.

Environmental mutagenesis·1987

Sister chromatid exchange analysis in lung and peripheral blood lymphocytes of mice exposed to methyl isocyanate by inhalation.

Environmental mutagenesis·1987

Uptake of germline testing for Lynch Syndrome in patients with deficient mismatch repair/ microsatellite-high colorectal cancer in the public hospital system in South Australia.

Familial cancer·2026

Unfinished Business and Experiences of Bereaved Families of Patients with Cancer: A Cross-Sectional Survey.

Palliative medicine reports·2026

Decoding RAGE in diabetes: a pathogenic signaling hub modulated by decoy receptors in diabetic complications.

Frontiers in clinical diabetes and healthcare·2026

Context-dependent modulation of the TAK1-MAPK axis by ginsenoside-based formulations along the NAFLD-HCC continuum.

Journal of ginseng research·2026

APOBEC3 activity and DNA polymerase-ε deficiency are associated with distinct IDH1 R132 hotspot mutations.

Molecular oncology·2026

Identifying multigenic modules under selection in the tumor genome.

Bioinformatics (Oxford, England)·2026

Related Experiment Videos

Dead cells don't form mutant colonies: a serious source of bias in mutation assays

Related Concept Videos

Bell-shaped nuclei dividing by symmetrical and asymmetrical nuclear fission have qualities of stem cells in human colonic embryogenesis and carcinogenesis.

Combination of competitive quantitative PCR and constant-denaturant capillary electrophoresis for high-resolution detection and enumeration of microbial cells.

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection.

Two-point fluorescence detection and automated fraction collection applied to constant denaturant capillary electrophoresis.

Identification of in vivo mutations in exon 5 of the human HPRT gene in a set of pooled T-cell mutants by constant denaturant capillary electrophoresis (CDCE).

Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene.

Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: observation of a positive response.

Mutagenesis of L5178Y/TK(+/-)-3.7.2C mouse lymphoma cells by the clastogen ellipticine.

Induction of sperm abnormalities in mice by quercetin.

The effect of cell passage on the susceptibility of BALB/3T3 clone A31-1-1 cells to 3-methylcholanthrene-induced morphological transformation.

Methyl isocyanate: an evaluation of in vivo cytogenetic activity.

Sister chromatid exchange analysis in lung and peripheral blood lymphocytes of mice exposed to methyl isocyanate by inhalation.

Uptake of germline testing for Lynch Syndrome in patients with deficient mismatch repair/ microsatellite-high colorectal cancer in the public hospital system in South Australia.

Unfinished Business and Experiences of Bereaved Families of Patients with Cancer: A Cross-Sectional Survey.

Decoding RAGE in diabetes: a pathogenic signaling hub modulated by decoy receptors in diabetic complications.

Context-dependent modulation of the TAK1-MAPK axis by ginsenoside-based formulations along the NAFLD-HCC continuum.

APOBEC3 activity and DNA polymerase-ε deficiency are associated with distinct IDH1 R132 hotspot mutations.

Identifying multigenic modules under selection in the tumor genome.

Related Experiment Videos

Dead cells don't form mutant colonies: a serious source of bias in mutation assays

Related Concept Videos

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