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Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis

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A highly optimized and sensitive bowtie shape-based SPR biosensor for different analyte detection.

Md Abu Huraiya¹, Sankar Ganesh Ramaraj^2,3, Sk Md Shahadat Hossain¹

¹Department of Electrical and Electronic Engineering, Rajshahi University of Engineering & Technology Rajshahi-6204 Bangladesh huraiyarueteee@gmail.com.

Nanoscale Advances

|December 25, 2024

Summary

This study introduces an optimized bowtie photonic crystal fiber (PCF) biosensor for highly sensitive refractive index (RI) detection. The PCF biosensor achieves superior performance, enabling precise detection of biological and chemical substances.

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Area of Science:

Photonics and Sensor Technology
Biomedical Engineering
Materials Science

Background:

Photonic crystal fibers (PCFs) are essential for advanced biosensor development.
Surface plasmon resonance (SPR) offers high sensitivity for refractive index (RI) sensing.
Optimizing PCF designs is key to enhancing biosensor performance.

Purpose of the Study:

To design and optimize a bowtie-shaped PCF biosensor for enhanced RI sensing.
To investigate the impact of structural parameters on sensor performance.
To demonstrate the potential of the optimized PCF biosensor for high-precision detection.

Main Methods:

Utilized finite element method (FEM) simulations in COMSOL Multiphysics v5.4.
Designed a bowtie-shaped PCF with optimized structural parameters (pitch, air hole diameter, gold layer).
Characterized sensor performance across a refractive index range of 1.32 to 1.44.

Main Results:

Achieved high wavelength sensitivity (WS) of 143,000 nm/RIU and amplitude sensitivity (AS) of 6242/RIU.
Demonstrated a high resolution of 6.99 × 10^-7 RIU.
Obtained a very high figure of merit (FOM) of 2600, indicating superior sensing capabilities.

Conclusions:

The optimized bowtie-shaped PCF biosensor exhibits excellent performance for RI sensing.
The design offers simplified fabrication and enhanced sensitivity.
The sensor is suitable for precise detection of various biological and chemical analytes.