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Updated: Jun 4, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Perceived harm of e-cigarettes relative to conventional cigarettes: Comparison among different measures in the US and
Thi Phuong Thao Tran1, Thi Tuyet Hanh Tran2, Thi Hai Phan3
1Georgia State University School of Public Health, GA, United States; Hanoi University of Public Health, Hanoi, Vietnam.
Introduction:
Evidence shows the inconsistencies in perceived harm of e-cigarettes between direct (single question) and indirect (assessing perceived harm separately by a single question and subtracting their score) measures. While the validity of both measures was tested by assessing their association with criterion variables (i.e., ever-trying e-cigarettes), further validation research is needed given existing limitations.
Methods:
We analyzed data from Population Assessment of Tobacco and Health Study Wave 6 in the US and a provincial version of the Global Adult Tobacco Survey 2020 in Vietnam. Comparative harm of cigarettes and e-cigarettes was measured using direct and indirect method. A new criterion validity measure - "I use e-cigarettes because they might be less harmful to me than smoking cigarettes" - was introduced.
Results:
In the general US population, a higher proportion of participants perceived e-cigarettes as less harmful than cigarettes when assessed using the indirect method compared to the direct method (31.56% vs. 13.70%). Additionally, although many US e-cigarette users indicated that they used e-cigarettes because they might be less harmful than cigarettes, among these people only 61.43% reported e-cigarettes to be less harmful when using the direct method but this proportion was higher (67.28%) for the indirect method. In Vietnam, this proportion was higher, at 76.68% using the direct method.
Conclusion:
This study emphasizes the significance of including and reporting multiple measures within a single survey to achieve a comprehensive understanding of perceived harm.
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